منابع مشابه
Glycemic equipoise
The term “equipoise,” defined as “a state of equilibrium,” is a noun as well as a verb.[1] Clinical (or community) equipoise, which implies that there is uncertainty among the medical fraternity regarding the benefit, or otherwise, of a clinical intervention, provides the basis for conducting clinical trials.[2] Equipoise is also used as a guiding tool for patient–physician interactions, which ...
متن کاملEquipoise in Clinical Trials
“Do you have equipoise?” The question was simple, yet loaded with challenges. We were being invited to participate in a prospective randomized controlled phase 3 trial testing whether acute endovascular stroke therapy can be beneficial for patients presenting beyond 6 hours from symptom onset (≤6 hours is the currently accepted therapeutic time window for mechanical thrombectomy) when using per...
متن کاملIn search of social equipoise.
Randomised controlled trials are common in medicine but less so in other fields. However, the use of trials in medicine is helped by an open acknowledgment of uncertainty about effectiveness—that is, clinical equipoise. In theory the same should also apply to social interventions (such as public policies), but no concept of “social equipoise” exists. This makes it politically difficult for poli...
متن کاملEquipoise and the technology curve
520 Freely available online open Access bJr bJr elimination of bias is a core element of high quality clinical trials. 1 In addition to selection, detection, attrition, reporting and spectrum bias, 2 a further type of bias has been reported, known as 'design bias'. 3 this occurs before the trial is begun and is inconsistent with the principle of 'equipoise' and has relevance for surgical trials...
متن کاملEquipoise and the criteria for reasonable action.
441 In her recent article, “Evidence, Belief, and Action: The Failure of Equipoise to Resolve the Ethical Tension in the Randomized Clinical Trial,” Deborah Hellman gives a new twist to an old objection against clinical equipoise.1 Roughly, clinical equipoise is the requirement that there exist credible uncertainty in the expert medical community regarding the preferred treatment for a particul...
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ژورنال
عنوان ژورنال: American Journal of Orthodontics and Dentofacial Orthopedics
سال: 2015
ISSN: 0889-5406
DOI: 10.1016/j.ajodo.2015.07.016